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SBI4U1 Biology
Notes for unit test on mendelian genetics You are responsible for all topics addressed in this unit. However, you may use the following list of topics to focus your studying: – DNA structure – Scientific contributions to the study of genetics: Franklin, Chargaff, Hershey & Chase, Griffith, Watson & Crick, Meselson & Stahl. – Structure and Organization of DNA: chromosomes, chromatin, histones, nucleosomes, supercoiling, exons, introns. – DNA Replication (enzymes involved, detailed steps, etc.) Protein Synthesis (Transcription/Post-transcriptional Modifications/Translation: stages, enzymes involved, types of RNA involved, structure of ribosome (P, A, E sites); I will give you the genetic code when needed in the question. Control Mechanisms in prokaryotic protein synthesis (terms: lac operon, trp operon, promoters, operators, inducers, repressors). – Mutations: missense, nonsense, silent, substition, deletion, insertion, frameshift, chromosomal, etc. – Biotechnology (Uses, Restriction Endonucleases/Enzymes, Gel Electrophoresis, Dideoxy Sequencing) CREATE NOTES AND MAKE SURE IT IS NEARLY ORGANIZED AND CREATIVE
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