You are required to respond to the initial responses of two of your classmates’ pitches with new information (along with supporting references) and personal experience being included in the responses.
CLASSMATE 1:
Based on the “Eureka! Moment” from primary article B, for a proper understanding of how plants and microbes work together to make crops more resistant to abiotic stress, it is important to learn more about how crops deal with stress. Many genes have been found that make plants more resistant to drought stress. A lot of different stress response genes and how they affect plants need to be looked at to figure out how drought tolerance comes from complex genetics (Bodhankar et al., 2020). It has been used to find genes that are more sensitive to stress. Different gene expressions under different conditions can help us understand how a biological system reacts to a certain situation.
Regarding the research, the study looked at how endophytic seed bacteria, which can help maize plants deal with drought stress if they are inoculated with them during sowing, affect the genes that make the plants more drought-sensitive. The endophytic bacteria used in this study came from surface-sterilized maize seeds of three different types of plants (Marag & Suman, 2018). The isolates might be able to help plants grow and grow better when they are under a lot of stress from drought.
I think this innovation is a fundamental contribution to life science due to the fact that millions of people still do not have enough food; it is very important that global food security be better. Net food producers may be able to benefit in the short term from high volatility and price spikes, which are both linked to crop output uncertainty and are bad for food security. Therefore, an innovation that focuses on endophytic seed bacteria, which can help maize deal with drought stress, could help solve the problem of food insecurity (Thiebaut et al., 2014). In well-managed, high-input systems, weather changes account for as much as one-third of the current crop output variability around the world. Hence, further research needs to know how climate change affects yield variability and average crop yields so that people can make smart decisions about farming.
References
Bodhankar, S., Grover, M., Mallappa, M., Reddy, G., Ghosh, D., & Mohapatra, S. (2020). The expression of selected drought-responsive genes of maize is influenced by endophytic bacterial inoculation. Journal of Microbiology, Biotechnology and Food Sciences, 10(2), 267-272.
https://office2.jmbfs.org/index.php/JMBFS/article/view/1762
Marag, P. S., & Suman, A. (2018). Growth stage and tissue-specific colonization of endophytic bacteria having plant growth-promoting traits in hybrid and composite maize (Zea mays L.). Microbiological Research, 214, 101-113.
https://www.sciencedirect.com/science/article/pii/S0944501318301307
Thiebaut, F., Rojas, C. A., Grativol, C., Motta, M. R., Vieira, T., Regulski, M., … & Ferreira, P. C. (2014). Genome-wide identification of microRNA and siRNA responsive to endophytic beneficial diazotrophic bacteria in maize. BMC genomics, 15(1), 1-18.
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-766
CLASSMATE 2:
I was most fascinated with the information provided in the article written by Mohammed Ali Khosravi and several others who contributed their own cells and/or DNA for the researching of fetal hemoglobin in sickle cell anemia. That was where my Eureka moment for my pitch idea occurred to me. One of the issues many regarding cell research are the difficulties that can occur dealing with cell culturing, cell health, and more. It is important to brainstorm for efficiencies in all processes and learn of benefits and risks.
The new innovation for my company is particular will be a specialized service of cell line management for the various needs companies who may require cell culture training or refreshing, process improvement, consulting with our experts, or any other issues that comes up with cell culture lines.
I would definitely support that my thoughts of innovation would contribute to the overall of life sciences for the progress of many different areas in the life sciences—specifically cancer research and gene therapy. Personally, I would argue that learning more about the cell processes—including blood work not only human as well as plant cellular processes would only help the creation of new innovation techniques used for improving the lives on the planet.
References:
1. Mohammad Ali Khosravi, et all. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease, European Journal of Pharmacology, Volume 854, 2019, Pages 398-405, ISSN 0014-2999,
https://doi.org/10.1016/j.ejphar.2019.04.042
2. Lorsch, J. R., Collins, F. S., & Lippincott-Schwartz, J. (2014). Cell Biology. Fixing problems with cell lines. Science (New York, N.Y.), 346(6216), 1452–1453. https://doi.org/10.1126/science.1259110
3. Evans, D.E., Coleman, J.O.D., & Kearns, A. (2003). Plant Cell Culture (1st ed.). Taylor & Francis. https://doi.org/10.1201/9781003076940
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