Problems:
1. (25 points): Implement the Needleman-Wunsch algorithm (NWA.py or NWA.m) using fixed -3 for
mismatches, 1 for a match, -2 for a gap.
2. (25 points): Implement another version of Needleman-Wunch algorithm (NWA_B62.py or
NWA_B62.m) using BLOSUM62 scoring matrix and -5 for gap. The BLOSUM matrix is available for
downloading at https://www.ncbi.nlm.nih.gov/
(https://www.ncbi.nlm.nih.gov/
3. (25 points) : Implement the anchored Needleman-Wunsch using BLOSUM62 matrix
(NWA_anchor.py or NWA_anchor.m) as it is described above.
4. (25 points) : Use the three algorithms to align the provided two pairs of sequences. Report the
alignment and the alignment score.
Homework 1_ Anchored Global Sequence Alignment slides hw1_files
APA
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The post 1. (25 points): Implement the Needleman-Wunsch algorithm (NWA.py or NWA.m) using fixed -3 for mismatches, 1 for a match, -2 for a gap. 2. (25 points): Implement another version of Needleman-Wunch algorithm (NWA_B62.py or NWA_B62.m) using BLOSUM62 scoring matrix and -5 for gap. The BLOSUM matrix is available for downloading at https://www.ncbi.nlm.nih.gov/Class/FieldGuide/BLOSUM62.txt (https://www.ncbi.nlm.nih.gov/Class/FieldGuide/BLOSUM62.txt) appeared first on Apax Researchers.